Details for gene set INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)
Enrichment Score (ES)	-0.7216553
Normalized Enrichment Score (NES)	-1.4411494
Nominal p-value	0.04204753
FDR q-value	0.61291087
FWER p-Value	1.0

Fig 1: Enrichment plot: INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS20	4540541 4730086	3690	0.242	-0.1647	No
2	RGS2	1090736	3979	0.182	-0.1548	No
3	RGS1	4060347 4540181	5139	0.069	-0.2074	No
4	RGS13	3780722	5280	0.063	-0.2061	No
5	RGS17	1400603	5836	0.044	-0.2298	No
6	RGS4	2970711	5956	0.041	-0.2305	No
7	RGS16	780091	7267	0.011	-0.2993	No
8	RGS11	2360041	8853	-0.015	-0.3824	No
9	RGS7	3390044	9297	-0.023	-0.4031	No
10	RGS18	1780019	10842	-0.055	-0.4784	No
11	RGS9	1050273	11785	-0.084	-0.5173	No
12	RGS6	6040601	15587	-0.637	-0.6328	Yes
13	RGS19	7050427	16348	-1.037	-0.5290	Yes
14	RGS3	60670 540736 1340180 1500369 3390735 4010131 4610402 6380114	16462	-1.101	-0.3814	Yes
15	RGS14	380086	16554	-1.165	-0.2238	Yes
16	RGS10	2340292	17905	-2.399	0.0382	Yes

Fig 3: INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING): Random ES distribution
Gene set null distribution of ES for INOH_NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)